Press Release

Osmetech PLC (“Osmetech” or “the Company”) (AIM:OMH) announces that it was notified on 23 December 2009 that Chris Gleeson, Non-Executive Chairman , purchased 29,426,608 ordinary 0.1p shares pursuant to the placing at 2.05p per share announced on 21 December 2009.

Mr Gleeson’s interest in the share capital of the Company following the placing is now 59,895,835 shares representing approximately 3.67% of the issued share capital of the Company.