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Electrochemical Detection Technology

 

 

 

 

Target DNA is bound to the gold electrodes on the cartridge via specific binding to the capture probe attached to the electrode by a selfassembled monolayer. The allele specific signal probe binds to the target sequence adjacent to the base of the capture probe, and the associated ferrocene labels are detected at the electrode surface by alternating current voltometry. This allows high specificity in a multiplexed geonotyping test

 

 

 

eSensor Cartrige

 

At the core of the eSensor detection technology are DNA fragments attached to electrodes on the surface of a small circuit board.  This DNA microarray is the basis of detection by the eSensor System for any DNA sequence.

Each electrode is electronically active and detects a different DNA sequence.  Finding the complementary sequence in the target DNA generates a characteristic electrical signal. 

Each eSensor DNA Detection System cartridge can detect several different DNA targets at once, providing a cost-effective platform for complex analysis.